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Cheap DSM to STL Flights

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Des Moines to St. Louis route information

Origin Airport Des Moines Intl.
Destination Airport Lambert-St. Louis Intl.
Airlines Serving American Airlines, Delta, United
Flight Price $172
Distance 259 mi

Cheap DSM to STL Flights

  • How long does it take to fly from Des Moines to Saint Louis?

    If you are flying on Southwest Airlines, your flight will be about one hour. So, if you were to leave Des Moines at 6:25 AM CDT, you would arrive in Saint Louis at 7:25 AM CDT.
  • How many flights are there per day from Des Moines to Saint Louis?

    Each day is different, but on average, you can expect to see five available departure times. You won't have as many options on this route as most others departing the United States.
  • What is the cheapest airline flying from Des Moines to Saint Louis?

    Delta Air Lines is offering the best deal at $178. Better reserve quickly because prices range all the way up to $737 over the next three months.
  • What is the cheapest day to fly?

    The cheapest day to fly from Des Moines to Saint Louis is on Tuesday. So, if you are trying to save a little cash on your next flight look for flights on that day.
  • Do some days of the week have more flight times than others?

    When you're flying from DSM to STL, the day with the most flight times is Monday, with six different options. Thursday currently offers the least amount of flight times with four options.
  • Which airline has the least delays from Des Moines to Saint Louis?

    Booking with FedEx means you will arrive to Saint Louis approximately the time you were supposed to. In fact, this timely airline has a 100% on-time average.
  • How long is the flight from DSM to STL?

    Southwest Airlines can get you there in one hour. So, if you were to leave Des Moines at 6:25 AM CDT, you would arrive in Saint Louis at 7:25 AM CDT. Just enough time if you want to catch up on your work before you land.

Des Moines to Missouri Flights

Sometimes you just need to get out of town or maybe you’re looking for a change of scenery. Regardless of the reason, a flight from Des Moines to Missouri will do just the trick! Go on, plan to see all the famous landmarks and eat your weight in the local cuisine. Your trip is beckoning, so answer the call by packing your suitcase and filling your travel itinerary with exploring Missouri.

Whether you’re flying for business or jet-setting on your personal time, you’ve come to the right place. Here at, we’ll pair you up with DSM to STL flights that won’t make your bank account wince. Ready to temporarily leave behind Des Moines for new horizons? Browse through our cheap airfare, and filter by flight times and dates until you find just what you had in mind. From flights without layovers to ones that arrive early in the morning, you’ll come across plane tickets that suit your travel preferences. You can even bundle your flight to STL with hotels and car rentals to score even bigger savings.

All set to hit the clouds? Book your travel arrangements with us today and have left-over money to put toward your travel outings and adventures.